In vitro, the inhibitory potency of fordine on mouse brain or erythrocyte AChE and on porcine brain immobilized AChE was thousand times higher than that on BuChE in the blood and serum of mouse. 它具有较强的拟胆碱作用。对小鼠脑、红细胞和猪脑固相胆碱酯酶(AChE)的抑制强度为对血浆胆碱酯酶(BuChE)抑制强度的数千倍。
The effects of Fordine ( a new AChE inhibitor) and placebo on 31 patients with impaired memory were studied using randomized double blind crossing medication and multiple selective verbal reminding tests. 采用随机双盲自身交叉给药,观察了一种新型胆碱酯酶抑制剂&福定碱对31例临床记忆功能障碍患者的疗效。